Memory Improvement Acetyl-L-Carnitine Hydrochloride Sell Online

Product name:Acetyl-L-Carnitine hydrochloride
Product Category:Health care products and pharmaceutical intermediates/Carnitine health-care products;
CAS No.:5080-50-2
Formula:C9H17NO4·HCL
MW:239.7
Characters:White crystalline powder
Property:hygroscopical,easily soluble in water
M.p.: 187-189

Health-Care Product Acetyl-L-Carnitine Hydrochloride 

Usage:

Pharmaceutical,nutrition food additives,improve memory, widely used to treat Alzheimer’s disease.

Product Content:
Acetyl-L-carnitine (ALCAR) is a drug currently under investigation for Alzheimer disease (AD) therapy.

ALCAR seems to exert a number of central nervous system (CNS)-related effects. The aim of this study was to determine cerebrospinal fluid (CSF) and plasma biological correlates of ALCAR effects in AD after a short-term, high-dose, intravenous, open treatment. Results show that ALCAR CSF levels achieved under treatment were significantly higher than the ones at baseline, reflecting a good penetration through the blood-brain barrier and thus a direct CNS challenge. ALCAR treatment produced no apparent change on CSF classic neurotransmitters and their metabolite levels (homovanillic acid, 5-hydroxyindoleacetic acid, MHPG, dopamine, choline). While corticotropin-releasing hormone and adrenocorticotropic hormone remained unchanged, beta-endorphins significantly decreased after treatment; plasma cortisol levels matched this reduction. Since both CSF beta-endorphins and plasma cortisol decreased, one possible explanation is that ALCAR reduces the AD-dependent hypothalamic-pituitary-adrenocortical (HPA) axis.

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